Characterization of Bacterial Pathogens of the Urinary Tract in Type 2 Diabetes Patients at Mzuzu Central Hospital, Nothern Malawi

People with type 2 diabetes are more vulnerable to infections due to a weakened immune system caused by diabetes-related factors. Urinary tract infections caused by bacteria are associated with antibiotic resistance and severe recurrent disease. This cross-sectional study characterized uropathogenic bacteria and assessed beta-lactamases linked to antibiotic resistance with a sample size of 294. UTIs were common in type 2 diabetics, especially in those with >190 g/dl mean RBS. There was a concerning 62.5% ESBL-producing E. coli that were resistant to antibiotics, which is a serious threat to public health. Thus, regular UTI screening and AST should be utilized before prescription to facilitate Antibiotic resistance surveillance and promote early diagnosis, treatment, and infection control.

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