Leveraging remnant viral load samples for SARS- CoV- 2 antibody seroprevalence trends among PLHIV in Kenya, February 2021–October 2022: a cross- sectional surveillance survey

A nationwide surveillance study in Kenya assessed SARS‑CoV‑2 antibody prevalence among people living with HIV (PLHIV) on ART using remnant viral load samples collected between February 2021 and October 2022. Results showed a sharp increase in seroprevalence from 16.1% to 91.7% across four survey rounds, indicating widespread exposure through infection and/or vaccination. Most antibody-positive samples (97%) reflected true prior exposure or vaccination. The findings highlight the extensive reach of COVID-19 among PLHIV and underscore the importance of continued surveillance, vaccination, and targeted prevention strategies to protect this vulnerable population.

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